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Mouse’s Liver Could Liver Forever

August 18th, 2008 · No Comments · Aging, Alzheimer's disease, Cutting edge medicine, insulin resistance, longevity, metabolic syndrome

mouse Anti-aging researchers in New York have successfully blocked the aging process in the livers of mice livers by impeding the build-up of harmful proteins inside the liver. This has tremendous implications for the extension of healthy aging.

As humans - and mice - age, the cells have more and more trouble disposing of damaged proteins. The damaged proteins produce a toxic buildup which damages, and eventually kills, the cell.

The lysosome is the ‘organelle’ within the cell which should digest the damaged proteins.


Normally, this ability diminishes with age. The scientists managed to maintain the youthful efficiency of the lysosomes even in mice which were the equivalent of 80 human years old.

This deterioration in cell function has been linked to the syndrome of insulin resistance as well as to neuro-degenerative diseases such as Alzheimer’s disease.

Extending the techniques used here and applying them more widely in the body could reduce or eliminate this source of cell death and so prolong healthy life.

Read More on Discovery News

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