Sirtuins May Hold The Anti-Aging Key… Or May Not

by Malc on February 20, 2011

Mitochondria - Damage Causes Aging

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Sirtuins excite various researchers – and consumers of pills – in the anti-aging movement.

The way this works, is that sirtuins are proteins produced by the SIRT1 and SIRT3 genes. In yeast, and later in roundworms, the situins have been found to extend life. Once this was discovered, ways were looked for him to increase the production of the sirtuins. After much research resveratrol – present in red wine – was identified as having this property.

However, not everybody is convinced that this is a viable line of research for anti-aging therapy.

For example, fightaging.org points out that “messing around with metabolic fixes” such as this is a distraction from the path towards proper anti-aging techniques. The site points out that the reason so much attention is focused on sirtuins is partly due to the huge amounts of money which had been poured into it.

A more promising line of research, the site opines, would be to investigate how  the damage to the cell’s mitochondria could be reduced over time. The mitochondria – which are the “powerhouse” – the energy source – of our cells.

Various lines of research point of this as being a more fundamental break on longevity than the than the effects of the sirtuins.

Here is the very interesting post:

Promising Line of Research for Anti-Aging

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