Study Questions Effectiveness of Calorie Restriction in Humans

by Malc on October 14, 2008

It is certain than Calorie Restriction (CR) in rodents extends their lifespan, as shown by numerous studies. Exactly how calorie restriction promotes longevity is not clear, though a low level of a factor in the blood called IGF-1 might be involved, it is thought.

To test this, researchers tested whether calorie restricted human had a low level of IGF-1, as restricted rodents have; they had not.

The researchers did confirm what was already known or suspected; a low intake of protein reduces IGF-1 levels.

Thus, if low IGF-1 does turn out to be an important factor in the longevity of calorie-restricted rodents, to emulate them, humans may need to carefully evaluate their own intake of protein.

Article at WordHealthNet


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