Best of all – it is completely free. David Kekich is doing all he can to publicize anti-aging, so is giving this book away. It’s a chunky tome – and packed full of information.

It tells you 7 steps to take to: “catch the emerging wave of medical breakthroughs…” for a healthy, extended life. I strongly recommend this book to help get you up to speed with the current state of anti-aging knowledge.

Also, follow author David Kekich on twitter @MaxLifeorg .

Free Longevity Book is a post from: Living To 150

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Gosh – I’d like to go to this – the Manhattan Beach Project, Los Angeles. It’s the conference I wanted to go to when I went to Convergence08 last November: because this on is focused specifically on longevity.

The field of longevity research is getting very exciting now. Aubrey de Grey is quoted as thinking there is a 50/50 chance of his living forever.  Now, if a conservative scientist says that, you have to take note.

Unfortunately, I cannot go – I have things booked for November and can’t get away. But it’s in the diary for next year.

Apparently there will be recordings of the speakers which can be watched for free.

“You’ll get to see all of the twenty minute presentations by world-leading researchers. Each one of the fifteen presenters will also answer up to ten minutes of questions.”

Sorry to miss it. The usual suspects – Aubrey de Grey and Ray Kurzweil – will be there (albeit Kurweil will be beamed in). The whole thing is hosted by David A Kekich and Greta Blackburn of Maximum Life Foundation, and sponsored by Life Extension Foundation. Should be very good.

Follow Maximum Life Foundation on Twitter @maxlifeorg .

Longevity Conference, November 2009 is a post from: Living To 150

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The pace of progress with stem cell research means that results can progress from project conception to clinic use in ten years – a very rapid time compared to conventional research.

These grants mean that we will be able to take advantage of this exciting technology that much faster.

California funds the biggest stem cell research programme in the world. This is thanks to Californian residents who voted the measure through in a referendum.

$60m Funding for Stem Cell Research is a post from: Living To 150

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(It’s said that the first person who will still be healthy at 200 is already living.)

So with that aim in mind I need to prepare myself for my trip to Denver, Colorado to see Terry Grossman, in July 2009.

What do I want to achieve?

Three main things.

1. Firstly, to have new blood tests taken, so that I can compare these with the ones I had done last year at Life Extension Foundation, and get the clinic’s views on them.
2. Secondly, to have a more detailed health assessment done, and so further review my health status.
3. Thirdly, to get the clinic’s views on my lifestyle, and how that is affecting my health, looked at against the backdrop of the blood tests.

New Blood Tests

It will be interesting to see how my blood test have changed compared to last year.

My main concerns with the blood tests were:

• High cholesterol. My total cholesterol was 235 mg/dl. This is about 6 in the UK measurement, and so about 30% too high. LDL and HDL were similarly high. However, my total cholesterol/HDL ratio was pretty good. Triglycerides were also good, at 72 mg/dl. (What is cholesterol?)
• Blood sugar. Fasting blood sugar was 102 mg/dl, or 5.6mmol/l in UK terms. Optimal is between 70 and 85.  So 102 is high. However, haemoglobin A-1 C was 5.6%, which is good. This is a measure of blood sugar over the past three-months. Also, fasting insulin was good at less than 2 mIU/dl.
• Hormones. My free testosterone was measured at 9.1 pg per millilitre. This is within the recommended range, but low within the range. Thyroid hormones again, were low within the normal range.

I will be looking to see whether the new blood tests reflect similar values to the old ones – from a year ago.

It will be interesting to hear the clinic’s personal recommendations. Last year I had only support via the telephone, which was not ideal. This one-to-one advice will be more helpful.

Preparing for My Health Review is a post from: Living To 150

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Short sighted journalists are fooled by profit-hungry drug companies who, as often seems to be the case, are driving partisan research chemists.

"Statins Reduce Heart Attacks"

This is not news, and it is not even surprising. Anything which reduces general inflammation in the body will reduce heart attacks. This includes Omega 3 fatty acids, and any number of herbs including nettles, ginger and turmeric. The problem with using statins instead is the many side-effects users have reported.

The New Trial

The new trial is clearly partisan. For a start, it is called ‘Jupiter’, which stands for Justify the Use of Statins… Hmmmh – little doubt about the results they are looking for, then.

The particular brand of statins it ‘justifies’ is Crestor, made by AstraZeneca which costs around £26 a month. As the predominant statins used in the UK are the generic Simvastatin which cost £1.42 a month, the trial results are great for AstraZeneca. No doubt certain sectors of the community will be calling for the replacement of Simvastatin with Crestor (is it me – or isn’t that also a toothpaste?).

Drug Company Strategy

Statins are the best thing that have happened to drug companies for a long time. They are turning into a license to print money. One prime benefit of selling statins is that they are being used by younger and younger people – and they ‘need’ them for life.

As the drug companies see their profits slashed by cheap generic replacements – they simply come up with a new twist – as in this case – to show, by a flawed study, the superiority of their new, replacement product. Then they get to milk it drug until the patent runs out.

This is exactly what they did with HRT (ERT); each time the evidence showed that HRT damaged health, new research unearthed a new supposed benefit of HRT so they could persuade doctors to keep prescribing it and journalists to keep writing about how good it was.

What To Do Instead Of Taking Statins

This trial was carried out by selecting people with a high level of c-reactive protein (CRP) in the blood. They were then given statins.

Agreed – CRP does indicate general inflammation in the body which gives a raised chance of heart and artery disease as well as of diabetes, various cancers and Alzheimers’ disease.

Where I don’t agree is the treatment. Drugs are not usually necessary.

To treat raised CRP a combination of herbal treatment and fish oils will usually bring it down. Take these, then recheck CRP in 2-3 months.

Ideally, CRP should be less than 0.5 mg/L (milligrams per litre) in men and less than 1.5 mg/L in women.

Avoiding Statins – or Coming Off Them

Don’t just stop statins if you are taking them. Come off them with professional guidance. Most certainly involve your doctor in this process. Similarly if you have been told that you need to take statins. Be cautious. Around 50% of people come off statins because of the side-effects; but don’t put yourself at risk by just not taking them – you need an alternative strategy.

1. The following link leads to an article which contains a list of 8 natural alternatives to lower cholesterol, based on sound science:
Natural ways to cut cholesterol

Extract from this article about avoiding statins:

"HOW TO AVOID STARTING STATINS
If your doctor advises you to begin taking a statin drug, suggest a lower dose or a delay in initiation of the drug until you have had two to three months to try natural cholesterol- and LDL-lowering agents. Patient involvement in treatment decisions is commonplace today, and most physicians will work with you. A rough rule of thumb: adherence to a low-fat, high-fiber diet (that eliminates processed foods), along with some of the nutritional supplements discussed in this article, will lower LDL cholesterol by as much as 30%. Keep this in mind when starting your program. …….." 

See the article for more detail.

2. This article covers the role of general inflammation in generating disease
Aging and Longevity – 4. Inflammation

Also, read Life Extension Revolution, by Miller, Chapter 7:  Cooling Inflammation: Disease-Proofing Your Body

Above all, don’t fall for the drug-company hype; because that’s what it is. In 2004 the pharmaceutical industry was estimated to be receiving $22 billion (£14 billion) from statin drugs.

Do your research and make your own mind up. And it’s not easy to get your CRP checked regularly – but is very, very useful to do so as it gives an early warning of problems to come.

Statins – Don’t Be Fooled By The Research is a post from: Living To 150

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A friend has hypertension, so I bought a blood pressure monitor to keep an eye on it.

After a week or so I took my own blood pressure and it was 110-115/65. Very low, thought I. Took it again, same. I thought I just wasn’t used to the machine. Waited a week and took it again.

Down, Down, Down

Yes, my blood pressure has come down. And I’m very happy because this correlates with increased health.

I haven’t recently taken up marathon running or any extreme sport; so I put it down to changes I have made in my diet this year.

I suppose taking Life Extension’s Life Extension Mix might have had an impact. But I think it’s more likely diet.

Dietary Changes

In my diet, I have: increased the raw food I eat – I have salad once or twice a day; almost cut out bread, potatoes, rice, pasta; increased nuts and seeds; almost cut out food cooked over 250 degrees F (about 110 degrees C).

I am really surprised at this reduction in blood pressure; but very pleased. I feel it is definitely a benefit of the changes in my diet.

Blood Pressure Down is a post from: Living To 150

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The researchers suggested that the spike in blood sugar was the mechanism which caused the reduction in drug absorption. In this case, other fruit juices will have a similar effect. (The previously identified interference of grapefruit juice with some drugs involves a different mechanism.)

The researchers advised drinking fruit juices 4 hours away from any drugs being taken.

Fruit Juice And Diabetes

The blood sugar spike caused by drinking fruit juice is also responsible

for the increased risk of diabetes they cause. Sugar is already pouring into the blood stream for most people. This comes from digested starches (bread, potatoes, rice, pasta) as well as from direct sugar sources – eg soft drinks. With extra sugar on top of this from fruit juices, the current dramatic rise in diabetes not surprising.

I advise:

• Avoiding drugs as much as possible, in general, and trying to use natural methods such as nutritional supplements and lifestyle changes
• Avoiding fruit juice – which increases the risk for diabetes. Whole fruit in moderation is fine – because the fibre reduces the spike.

If you take these two actions, then the finding from this study need not be a concern.

Mail Online coverage of the study
Life Extension Foundation comprehensive article on Diabetes

All Fruit Juices Can Interfere With Drugs is a post from: Living To 150

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This is not surprising – because statins lower inflammation; and there is a link between Alzheimer’s disease and low-level inflammation. 

However, the solution to low-level inflammation is NOT to take statin drugs. Just as the answer to cholesterol is not to take statin drug – except in isolated cases.

Measuring Low Level Inflammation

Currently, the best and cheapest way to find out if you have a raised level of low-level inflammation is to measure c-reactive protein, or CRP. This substance has a raised level if inflammation is present. This blood test is simple and not expensive.

Treatment

If CRP is high, treatment to lower inflammation is a combination of herbs and nutrients. Some important options are:

- Fish oils/Omega 3 fatty acids
- The ‘master hormone’ DHEA
- Bromelain – from pineapple
- Nettle leaf
- Ginger
- Turmeric

For more details, check out Philip Miller’s excellent book: "Life Extension Revolution", p 191.

Alzheimer’s treatment protocol

And – as a general rule – don’t take the statins!

Statins & Alzheimers – Right For Wrong Reason is a post from: Living To 150

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The reason I hate to report it, is because many people will be as shocked as I was – or even disbelieving – when first hearing that their morning ‘health’ drink could actually be unhealthy.

But it is true.

The Whole Fruit, Nothing But The Fruit

All fruit juices are similar to sugar water. True, the sugar is not glucose; it’s fructose. But it still spikes up blood sugar after drinking it.

The whole fruit contains fibre which slows sugar absorption down. The juice has most or all of the fibre removed so that the passage of sugar into the blood stream is rapid.

The Path To Diabetes (type II)

The 3-step pattern leading to diabetes can then emerge:

1. Sugar in the blood demands insulin, from the pancreas. Insulin influences ‘receptors’ in the cell walls to allow sugar to pass inside.
2. Over time the cell wall receptors become less responsive to repeated insulin insults. The pancreas has to produce more and more for the same result.
3. The overworked pancreas becomes can’t keep up with the demand for insulin. Blood sugar builds up and diabetes is present.

Avoid Diabetes – And Delay Aging

A feature of diabetes is that sufferers get aging diseases much earlier than the rest of us.

This is why diabetics tend to get problems with heart and arteries, kidneys and eyes at a relatively young age. Control of the diabetes is essential; and for most, perfectly possible.

Control Through Diet

Although input from an experienced practitioner is always helpful, one of the main approaches to dealing with Type II diabetes (also called ‘maturity onset’ diabetes) is through a rigorous diet.

This is the same diet as a ‘healthy aging’ diet, but with more care taken to keep blood sugar low.

This means reducing intake of sugar and starches (mainly potatoes, pasta, rice and bread) dramatically such that your blood sugar remains at a low-normal level – not just a moderate level.

Blood sugar can be monitored through regular blood tests.

A practitioner can advise on supplements to be used. Also see:

• Life Extension Foundation – diabetes for a great article
• Life Extension Magazine August 2008, p67 "Metabolic Disease and Heart Attack, which is very relevant. 
• www.meta-syndrome.com for information on Metabolic Syndrome.

Finally, here is:

• A report of the Orange Juice study

Orange Juice Gives You Diabetes is a post from: Living To 150

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One of the websites I go back to again and again is that of Life Extension Foundation. If you have a health condition and you want to find a treatment protocol for it, you can probably find one on their website.

The treatments recommended include prescription drugs where these are appropriate for consideration as well as recommendations for supplements and herbs. All recommendations have references to studies validating the benefits cited.

A highly recommended site to help you understand how the body works, and how disease processes develop and how you can treat them.

Great Health Research Site is a post from: Living To 150

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Systemic inflammation is when there is general ‘background’ inflammation without pain or symptoms – at least initially. For this reason it is insidious as it can just creep up on you. The joints and muscles can slowly degenerate without you realising it.

The same inflammation is a major cause of a host of other diseases including heart and artery disease; some cancers; Alzheimer’s disease, as well as conditions due to thickened blood such as angina and clouded thinking.

Systemic inflammation can be indicated through blood tests for C-reactive protein (CRP) and fibrinogen. If both of these are low, this is a good sign that systemic inflammation is not rampant in your body.

My own measures for these two are: CRP – 0.82 mg/L, and 149 mg/dL of fibrinogen. The ‘reference range’ (range within which the lab suggests the results are ok) for CRP is 0-3 mg/L and for fibrinogen 193-423 mg/dL.

This makes my CRP within the good range; but I think .5 is even more desirable than .82 (says Philip Miller).

My fibrinogen level is lower than the reference range. The lab’s doctor says this is a good thing. I wonder why it is so low. High fibrinogen thickens the blood; low fibrinogen should thin the blood. This might be expected to make me bleed more easily, which I do not experience – at least not yet  

Systemic inflammation is one of the 4 key ‘-ations’ identified by Philip Miller (Life Extension Revolution, Ch 7) as being crucial to address if you wish to achieve healthy aging.

Treatment is simple; change your diet to exclude inflammatory factors (such as Omega 6 fatty acids) and take a mixture of herbs including:

• Nettles
• Circumin (Turmeric)
• Ginger

and supplements, including:

• DHEA
• Vitamin K
• Bromelain

Then you need to retest the blood to see if what you did worked. A lot of hassle, but it’s worth it to help avoid degenerative diseases.

Afterwards, an annual blood test will check everything is still ok. This should be part of a regular health routine.

Arthritis and Inflammation is a post from: Living To 150

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I have taken Life Extension Foundation’s Life Extension Mix (a very special multi-mineral/vitamin mix) for around 6 months. I did this on purpose prior to taking the blood tests. This may well have boosted levels of certain blood components up to their current good levels.

Eg, chromium, zinc and selenium are often found to be deficient; my chromium and zinc were fine; the selenium I don’t know because that was the one test which did not come out for technical reasons.

My 3 aims for treatment now are:

A reduction in fasting glucose levels. (Because of the generally damaging effects on the body of any more than a low level of blood glucose)

A reduction in total cholesterol. Mine is 235mg/dL (6mmol/L), and the target is around 180mg/dL (4.6mmol/L).

A reduction in C-reactive protein (CRP). Mine is good at .82mg/L; ideal is less than 0.5mg/L. CRP is a strong indicator of low-grade inflammation in the body which promotes heart and artery disease, cancers and arthritis.

Next – my programme to achieve these aims.

Aims Of Treatment For Longevity is a post from: Living To 150

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I will get as far as I can in improving my test results, and then consult a life extension specialist to go further.

The Tests Which Were Done

I’ve had just over about 60 tests carried out by Life Extension Foundation. These are to test:

• The sugar in the blood/insulin response
• Kidneys
• Liver

• Electrolytes
• Cholesterol and triglycerides
• Homocysteine (heart and artery health)
• Prostate
• Some hormones – Testosterone, DHEA, Estradiol
• C-Reactive Protein (indicates ’systemic inflammation’)
• White and red blood cell numbers and shapes
• Thyroid hormones – 3 tesets
• Vitamins B12, D
• Hemoglobin A1c (test for ‘glycation’ – which causes wrinkling of skin and vital organs)

I will talk about the results next post.

Blood Tests For Longevity – Details Of Mine is a post from: Living To 150

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…we know that the key to beating disease is to respond to early signs of cellular dysfunction, long before the first sign or symptom appears. While full-blown disease is often unstoppable, the cellular mechanisms that begin the disease process are relatively easy to influence. By quenching these tiny sparks, we can prevent the fires from igniting.

The value of blood tests is in the early warning they can give before signs and symptoms turn into diseases.

Interpreting the results might be easier than you think. For example, the results of my first blood test surprisingly identified high cholesterol. The lab made it simple for me by putting the desired range in one column, and writing ‘high’ next to it for me to see clearly.

And now I know it is so, I can do something about it before it produces heart and artery disease.

Why Excellent Blood Tests Are So Important is a post from: Living To 150

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Life Extension Foundation (LEF) in Ft Lauderdale, Florida, offer very reasonable prices for blood tests. In addition, every year they have a sale when prices are even cheaper. LEF can arrange to take your blood all over the USA.

Living in the UK, I searched around for labs who offered a similar analysis, but with little luck. I later heard of one which probably could do; but I have no doubt they would be much more costly. LEF charged me less than £250 ($500) for around 50 tests.

They seemed to take a ton of blood – 6 vials of the stuff; but I didn’t stagger out of the lab, so it obviously was not too much.

While I was in Florida I thought I should allow a few days rest to adjust to the jet lag. I enjoyed the lovely warm weather, the local bars, and learned to scuba dive.

The test results have now arrived by post. And yes – there are some concerns as well as some reassuring signs.

My plan is:

1. Interpret the results as best I can, using books, Internet, and LEF’s free telephone advice service.
2. Devise a treatment plan
3. Retest and re-assess.

When I come across something I cannot improve, or when I have done all I can, I will seek professional help. I am currently leaning towards consulting Philip Miller (author of Life Extension Revolution) in California.

Good Blood Tests are Vital is a post from: Living To 150

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He points out that white blood cells are closely involved in arteriosclerosis, cancer, arthritis and Alzheimer’s Disease, for example.

He also has observed that aging takes place in ’spurts’, rather than steadily. He aims to help us to reduce these ’spurts’ to a minimum in his book Ultra-Longevity.

One way to see the level of immune system overactivity is to measure C-reactive protein (CRP) in the blood. This should be at or below 1.5 mg/L for women and 0.6mg/L for men. (Philip Lee Miller, Life Extension Revolution.) If you are having blood tests taken to assess overall health, CRP should certainly be one of them.

Take Liponis’ light-hearted quiz to find out how your immune system scores out of 100.

Immune System – Key to Aging? is a post from: Living To 150

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