Transplants Extend Human Lives

by Malc on January 18, 2012

Diseases and conditions where stem cell treatm...

 

When the first heart transplant was carried out it was a startling event. But fantastic as it was, the poor patient had to exist on immunosuppressant drugs for the rest of his life. Okay, he was still alive; but his immune system was severely compromised, making it difficult for him to cope with any infections.

 

In the meantime, more and more body parts have been produced using a patient’s own tissue, thus negating the need for immunosuppressant drugs.

 

Several wind pipes are now being grown from scratch and transplanted into patients using their own stem cells. These have produced dramatic improvements in health without any need for drugs to suppress the immune system. Similarly, the bladder and urethra have been grown using stem cells and transplanted into patient successfully.

 

Aubrey De Grey, anti-ageing specialist, recently commented: “We are seeing the emergence of a new area of medicine where the diseases of ageing can be blocked or even reversed. These therapies are mostly in research now but eventually they will be commonplace.”

 

Even a decade ago, these procedures were regarded as on the very margins of research. They are now rapidly becoming mainstream. Regenerating more complex organs is going to take longer – but they will be developed, it’s just a matter of time.

 

Hearts, kidneys and livers will be able to be grown, sooner than we think. And knees and hips will be regrown by using stem cell therapy. Even clinical trials for regeneration of spinal cells are under way.

 

These are exciting times for regenerative medicine, and its benefits will be with us at an ever-increasing rate.

 

 

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Cancer Cure in Sight in 5-10 Years

by Malc on January 18, 2012

English: Nobel laureate Dr. James D. Watson, C...

It is illuminating to think back to the 1920’s when very many were still dying from the effects of bacterial infections – tuberculosis, syphilis, gonorrhoea, blood poisoning.

If you had told people back then that these diseases would be virtually wiped out within a decade, you would have been greeted with ridicule. But, penicillin was discovered – and they were wiped out.

James Watson is one of the giants of 20th century biology. Along with Francis Crick, he predicted accurately the structure of DNA to be a double helix.

Well, Watson is still active in research at the age of 83. His interesting prediction is that the back of most cancers will be broken within 5 to 10 years.

There is still a lot of fear around cancer. But just think that most cancers could, according to Watson, be curable by 2022.

The thing is, there are pathways through which cancer is able to multiply itself indefinitely – at least, it can now. But once these are found, then blocking these pathways will clobber any cancer easily.

Today, it’s hard to accept that. But it was equally hard for people in the 1920’s to imagine the effects of penicillin on bugs which had been killing a large proportion of the population for generations.

Hard as it is to accept, cancer is now on the run.

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Viral Liver Failure Avoided By Injection

December 5, 2011

In world first, a baby boy in London was saved from death due to a virus affecting his liver, by having donor liver cells injected into his abdomen. These injected cells were able to perform many of the functions his stressed liver could not, enabling him to live long enough for his body to fight [...]

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Identifying the Precise Genome of the Black Death

November 28, 2011

The Black Death, which swept through London in the 14th century, killed around 40% of the population. That was some epidemic. In an effort to understand microbial development and behaviour, with a view to helping us to deal with future infections, the science of paleomicrobiology has developed: the piecing together of genetic evidence from centuries [...]

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Stem Cell Trial To Help Blind

September 28, 2011

Embryonic stem cells are to be used to treat blindness in the first trial of its kind outside the United States. The trial, taking place at Moorfields Hospital in London, will treat sufferers from a disease causing blindness at a relatively young age – Stargardt’s disease. The findings from the trial will have wider application, [...]

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New Arthritis Drug Offers Hope

September 28, 2011

New potential benefits for arthritis from an existing osteoporosis drug have been identified following a study carried out on mice. The drug was shown to thicken cartilage by over 30% – a good first result. This new use for it was identified by US researchers, working with mice. There is no evidence as yet that [...]

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Trial Of Heart Attack Stem Cell Treatment

September 27, 2011

Stem cells are being tested to improve the success rate of certain heart attack treatments. If a blocked artery causes a heart attack, a common treatment is to insert a stent – a hollow tube – into the artery to re-enable the blood flow. The problem is that the insertion of the stent can cause [...]

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What Use Is Genetic Testing?

August 12, 2011

Genetic testing – sequencing the genome – will be used more and more for individuals – and health services – as the price comes down. The cost is now around $10,000, down from $100,000 only two years ago.  In a very few years the cost will be hundreds of dollars. But what will we be [...]

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Incredible! The First Synthetic Windpipe

August 12, 2011

In 2008, a woman in Italy with a windpipe ravaged by tuberculosis received a windpipe transplant. A donor windpipe was stripped of all cells, leaving just the cartilaginous framework, then the woman’s own stem cells were introduced to produce a complete windpipe. The transplant was a success. Then, in 2010, a child with a congenitally [...]

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Is The NHS Ready For Genetic Medicine?

August 7, 2011

Ten years after the human genome was sequenced, the UK National Health Service (NHS) is ill-prepared to deal with the benefits. A report by Sir John Bell states that “There has already been a lot of innovation almost none of which has been adopted by the NHS.” I suppose this should not be too surprising: [...]

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